England slipped to 131 for four at tea on the first day of the must-win third Test against the West Indies on Friday.
Jason Holder was vindicated for his decision to insert England in the deciding Test match in Manchester, with Ollie Pope and Jos Buttler taking the hosts through to the final session.
Kemar Roach claimed the big wicket of Ben Stokes, bowling the England batsman through the gate for 20, before Rory Burns fell for 57 to the part-time spin bowling of Roston Chase.
Roach had struck in the first over of the day, dismissing second Test centurion Dom Sibley for a fifth-ball duck.
The opener was plumb LBW after being caught on the crease by a full ball from the West Indies quick.
That brought Joe Root into the crease at No 3 after he was bumped up the order with Zak Crawley missing out due to the thigh injury that has restricted Stokes to a batting role in this Test match.
After their bright start West Indies were dealt an early blow when Shannon Gabriel was forced from the field due to injury in just his fourth over.
West Indies had already dropped Alzarri Joseph for spin bowler Rahkeem Cornwall, and were left with just Holder and Roach as pace options.
But Gabriel was able to return to the field of play to bowl the 21st over and went on to complete another four overs.
Rory Burns and Joe Root looked to have settled the hosts down before the England captain was run out for 17 by a direct hit from Roston Chase.
England will continue after lunch with Burns unbeaten on 33 and Stokes on seven.
Earlier England recalled Jofra Archer and Jimmy Anderson in place of Crawley and Sam Curran after being forced to rejig their batting lineup due to the thigh injury suffered by Stokes during his heroic efforts in the second Test.
England plumped for Archer despite fears over his mental health after the racist abuse he suffered when he was dropped for the second Test after breaking the bio-secure regulations.
Archer revealed in an explosive Sportsmail column on Wednesday that he had been racially abused on social media and believed he had been treated ‘like a criminal’ after breaching bio-secure regulations en route from Southampton to Manchester after the first Test.