Scientists are perplexed after lab-grown “mini brains” develop “light-seeing” EYES.
SCIENTISTS were perplexed when lab-grown “mini brains” formed basic eye structures and began “seeing” light.
The wonderful, yet strange, accomplishment was accomplished on human-derived brain organdies, which are miniature copies of organs that can be created in a lab from stem cells. Scientists have previously built miniature beating hearts and tear ducts capable of crying like people. Researchers at the University Hospital Düsseldorf have taken an even creepier step forward by creating “little brains” with a collection of eye-like structures known as “optic cups.” .
The retina delivers messages to the brain via the optic nerve in the human body, allowing us to view images — and scientists appear to have recreated this.
“In the mammalian brain, nerve fibres of retinal ganglion cells reach out to interact with their brain targets, an aspect that has never before been proven in an in vitro system,” stated senior author Professor Jay Gopalakrishnan.
The organoids created these optic cups once the stem cells matured into micro brains.
According to the statement, the amazing development appeared as early as 30 days and matured within 50 days, a timeframe close to how the retina develops in a human embryo.
The researchers made 314 micro brains in all, with 72 percent of them forming optic cups.
Different types of retinal cells generated active neuron networks that “responded to light” in the organoids.
“Our work demonstrates the astonishing potential of brain organoids to form rudimentary sensory structures that are light sensitive and harbor cell types comparable to those present in the body,” Prof Gopalakrishnan said.
The research is being done to learn more about human brain development and disorders.
The organoids could one day be used to study the brain-eye relationship during embryo development, according to the researchers.
They could also be utilized to research retinal diseases and possibly develop personalized retinal cell types for therapeutic purposes.
“Optic vesicle-containing brain organoids displaying highly specialized neuronal cell types can be generated, paving the path for the development of customised organoids and retinal pigment epithelial sheets for transplantation,” the researchers said.
“We believe [these]are next-generation organoids that can be used to represent retinopathies that arise from neurodevelopmental problems in children.”
It follows the birth of a miraculous baby shark in Sardinia, Italy.
There hasn’t been a male in the tank in almost a decade, according to aquarium staff.
Scientists were taken aback, believing it was impossible. “Brinkwire News in Condensed Form.”