AstraZeneca makes history as the UK company celebrates the results of another another wonderdrug discovery.
After the findings of a pharmaceutical study showed that it was highly effective in treating a genetic illness, ASTRAZENECA has discovered a potential rare diseases wonderdrug.
In a phase 3 trial, the drug for Wilson’s illness was found to be three times more effective at removing copper deposits than traditional therapy. The study involved 214 individuals, including those who had never had treatment before and those who had been on alternative therapy for an average of ten years or more. Wilson’s illness is a hereditary ailment that affects the body’s capacity to eliminate excess copper.
Toxic copper build-up can cause liver disease, as well as psychological and neurological issues like personality changes, tremors, and difficulties walking, swallowing, or speaking.
The major purpose of the study was to improve the daily mean copper mobilized from tissues throughout a 48-week period.
The once-daily oral drug could be a less invasive alternative for individuals who are currently receiving therapies that include blood injections of a metal-removing solution or zinc therapy.
To help speed up development, the medicine has been designated as a “Orphan Drug” in the United States and the European Union.
The wonderdrug was acquired by AstraZeneca courtesy to Alexion’s $39 billion (£28.45 billion) purchase last month.
It is the drugmaker’s largest acquisition since it was formed in 1999 by the merging of Astra, a Swedish pharmaceuticals firm, and Zeneca, a British pharmaceuticals company.
AstraZeneca has now entered a fourth therapeutic area, which is defined as a grouping of comparable diseases or disorders under a single category.
“Where previous treatments remove copper from the blood, these 48-week results reveal its tremendous impact in mobilisation copper from tissues,” said Marc Dunoyer, 68, former AstraZeneca chief financial officer and now CEO of Alexion.
“We will continue to follow these patients long term to measure clinical impact on illness symptoms as we pursue this first innovation in Wilson disease treatment in more than 30 years,” says the researcher.
Alexion had previously stated that the treatment for Wilson’s illness had a peak sales possibility of between $500 million and $1 billion, according to Adam Barker, an analyst at Shore Capital.
Alexion was acquired by AstraZeneca last month, and the company wants to increase sales of Alexion’s rare disease medications around the world.
This is particularly true in China, which is rapidly becoming a significant market for AstraZeneca.
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