The vast majority of MPs voted in favour of the Brexit bill, paving the groundwork for the EU deal.
The law will now be debated this afternoon by the House of Lords.
With 521 in support and 73 opposed, MPs voted in favor of the bill – a majority of 448.
Following the outcome, the SNP said Scotland had been “ignored” and believed independence was the only way forward for the nation now.
After abstaining from the vote on the Brexit deal, Shadow Cabinet minister Helen Hayes resigned from the Labour frontbench.
She tweeted, “I am grateful to everyone who contacted me regarding the EU Future Relationship Bill. I cannot vote for this damaging deal and have abstained today. It is with much sadness and regret that I have offered my resignation as Shadow Cabinet Secretary. It has been a privilege to serve.”