Migraines reduce the incidence of type 2 diabetes through controlling insulin, according to a recent study.
Type 2 diabetes is characterized by high blood sugar levels and insulin resistance. According to a new study, migraine sufferers have a much lower likelihood of developing the condition, while diabetics become less prone to migraines. How?
Type 2 diabetes is a condition in which the body’s insulin secretion is drastically slowed. Insulin is a hormone that controls blood sugar, which is the most common kind of sugar in the body. If left to its own devices, blood sugar levels will continue to rise, causing a slew of negative consequences. An intriguing association between migraines and type 2 diabetes has been discovered in a new study.
According to a new study, migraine sufferers are less likely to develop type 2 diabetes, while diabetics are less likely to suffer from migraines.
Scientists investigating the link between these disorders have discovered that the peptides that trigger migraine pain can affect insulin production in mice, either by controlling the quantity of produced insulin or boosting the number of pancreatic cells that make it.
These discoveries may help to enhance diabetes prevention and treatment strategies.
“Migraines affect the brain, whereas diabetes affects the pancreas, and these organs are located far apart,” said Dr Thanh Do, the project’s primary scientist.
After reading a number of publications that indicated an inverse link between the conditions, his group became interested in the subject.
Researchers have previously discovered that two peptides contained in the neurological system play a key role in the pain caused by migraines.
The pancreas produces calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide (PACAP), which regulate insulin secretion from beta cells.
Insulin helps other cells in the body absorb glucose and store or use it for energy, thereby regulating blood sugar levels.
These other cells become resistant to insulin and less capable of absorbing glucose in type 2 diabetes, resulting in elevated blood sugar levels.
The beta cells adjust at first by increasing insulin production, but they gradually wear out and die, worsening the problem.
Because of their roles in migraine and diabetes, CGRP and PACAP are potential targets for treatments to treat both of these diseases.
Dr. Do and his colleagues at the University of Tennessee found a method to harvest data from just a few peptides to investigate their function in migraines and diabetes. “Brinkwire News in Condensed Form.”