A new study suggests that statins may improve survival from aggressive cancers.
SOME cancers, such as triple-negative breast cancer, are resistant to standard chemotherapy, making them more likely to spread and become incurable sooner. Patients with aggressive breast cancer may benefit from cholesterol-lowering statins, according to researchers.
Breast cancer affects one in every seven women at some point in their lives, yet it is mostly avoidable. Every year, around 8,000 women are diagnosed with triple-negative breast cancer, which is one of the most difficult types of breast cancer to cure. However, researchers believe that people who take statins have a better chance of surviving an aggressive form of breast cancer.
Triple-negative breast cancer is a rare type of cancer that is often more aggressive and difficult to treat than other types of cancer.
Currently, the only options for treating these tumors are surgery, radiation, and chemotherapy.
“There is already a corpus of literature on statins and breast cancer, and the outcomes have been inconsistent,” said Kevin Nead, principal researcher from the University of Texas.
“Previous study has focused on breast cancer as a single disease, but we know there are various subtypes of breast cancer, and we wanted to focus our research on this especially aggressive kind of breast cancer with few viable treatment options,” says the researcher.
Caffeine’s health benefits: how it can lessen your cancer risk
The malignancy is known as ‘triple negative’ because it lacks three components known as receptors, which are abundant in many breast cancers and provide useful targets for treatment development.
Researchers looked at data from 23,192 breast cancer patients, focusing on those who started taking statins within a year of their diagnosis.
Researchers discovered that up to 58 percent of those patients had a better chance of surviving their breast cancer.
Women with early-stage triple-negative breast cancer who were taking a high dose of statins had the highest link between survival and statins.
Patients using lipophilic statins, such as atorvastatin, simvastatin, lovastatin, and fluvastatin, had greater overall survival rates, according to the study.
Although it’s unclear how statins could improve breast cancer patients’ survival rates, earlier research has showed that they may reduce heart muscle damage induced by chemotherapy, which could improve overall survival rates in the years following recovery.
“We know that statins reduce breast cancer cell division and enhance cell death,” Nead continued.
“According to our findings, there is a link between statins and heart disease.”Brinkwire Summary News”.