According to a new study, pregnant women who are infected with Covid-19 are unlikely to pass the virus on to their babies.
Anti-coronavirus antibodies were passed from mother to child through the placenta at a considerably lower rate than anti-influenza antibodies.
Pregnant women may be more susceptible to acquiring severe Covid-19 infections after infection, but little is known about their anti-coronavirus immune response or how it may influence their child. An analysis has now revealed fresh information that could aid in the betterment of treatment for these moms and their newborns. According to studies, pregnant women infected with SARS-CoV-2, the virus that causes Covid-19, during the third trimester are unlikely to transfer the infection on to their newborns.
The researchers looked at levels of virus in respiratory, blood, and placental tissue samples, as well as the development of maternal antibodies, how well those antibodies passed through the placenta to the fetus (an indicator of potential immune protection from the mother), and examined placental tissue.
Between April 2 and June 13, 2020, the authors followed 127 pregnant women who were admitted to Boston hospitals. There were no SARS-CoV-2 positive infants among the 64 pregnant women who tested positive for the virus. Despite finding the virus in the women’s respiratory system, the investigators found no virus in maternal or cord blood. They also discovered no indication of viral transmission to neonates or symptoms of the virus in placentas. The researchers believe that transmission to the fetus is hampered not only by the lack of virus in the mothers’ blood, but also by the fact that the primary molecules utilized by SARS-CoV-2 to enter cells (ACE2 receptor and TMPRSS2 enzyme) are frequently not physically present in the placenta.
Dr. Diana W Bianchi, director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, says, “This study provides some reassurance that SARS-CoV-2 infections during the third trimester are unlikely to pass through the placenta to the fetus, but more research is needed to confirm this finding” (NICHD).
Dr Andrea Edlow, a maternal-fetal medicine specialist at Massachusetts General Hospital and an assistant professor of obstetrics, gynecology, and reproductive biology at Harvard Medical School, conducted the study, which was published in the journal JAMA Network Open. Because data on women infected during the first and second trimesters is still being collected and assessed, the outcomes given are confined to women in their third trimester.
As of December 21, the US Centers for Disease Control and Prevention (CDC) had received reports of 49,036 Covid-19 instances among pregnant women in the US, including 60 deaths. Only hospitalization data for 40,580 (82.8 percent) pregnant women is available, and it shows that 9,074 were admitted owing to coronavirus. Brinkwire News in a Nutshell